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The mitochondria is the powerhouse of the cell and is responsible for producing energy through cellular respiration. This process is crucial for cell metabolism, meaning the chemical reactions that occur within a cell to sustain life. Option B, the vacuole, primarily serves as a storage space for water, nutrients, and waste products. Option C, the Golgi apparatus, is involved in packaging and transporting proteins. While important for cell function, it does not directly control cell metabolism. Option D, the lysosome, is responsible for breaking down and recycling cell waste and is not involved in controlling cell metabolism. Therefore, the correct answer is option A, mitochondria.